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硫酸镁与一氧化氮治疗新生儿肺动脉高压临床疗效比较 被引量:9

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摘要 目的:观察硫酸镁(MgSO4)静脉滴注和一氧化氮(NO)外源吸入治疗新生儿持续肺动脉高压(PPHN)的临床疗效。方法:回顾性分析2006年9月~2008年1月临床诊断为PPHN的32例患儿,其中10例应用MgSO4静脉滴注治疗,22例应用NO吸入治疗。所有患儿分别于治疗前、后监测肺动脉压力(SPAP)、动脉血氧分压(PaO2)及体循环收缩压(SBP)的变化。结果:MgSO4静脉滴注、吸入NO60~120 min、24~48 h及治疗结束后的SPAP、PaO2与治疗前相比有显著性差异。但MgSO4静脉滴注组SBP明显下降,与治疗前相比有显著性差异;NO吸入组SBP无明显下降。结论:静脉滴注MgSO4和外源性吸入NO均可有效治疗新生儿肺动脉高压,但NO吸入起效更迅速、安全,且具有高度肺血管选择性。
出处 《中国妇幼保健》 CAS 北大核心 2009年第7期935-936,共2页 Maternal and Child Health Care of China
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参考文献8

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