摘要
目的观察和比较膀胱移行细胞癌术后应用丝裂霉素和吡柔比星做膀胱灌注的疗效。方法将我院2002年3月至2008年3月手术后的83例膀胱移行细胞癌患者随机分为两组:丝裂霉素组44例,吡柔比星组39例。术后1～2周开始灌注,比较复发率。结果随访3个月～6年,平均28个月,复发15例。丝裂霉素组8例,复发率为18.2%;吡柔比星组7例,复发率为17.9%。结论两种化疗药做膀胱灌注治疗,对预防膀胱移引细胞癌术后复发,差异无统计学意义。
Objective To observe and compare the clinical efficacy of postoperative intravesical instillation of MMc and THP for prevewting recurrence of transitional cell carcincrma of bladder. Methods Eighty - three cases of transitional cell earcinorma of bladder dmitted our hospital from March. 2002 to March. 2008 were seperated randomly into groups： MMc group （44 cases） and THP group （39 cases）. 1 -2 weeks after surgical operation, intravesieal instillation was used and the cancer recurrence rate were campared between two groaps. Results All the 83 patients were followed up for 3 months to 6 years. An average time of 28 months. In MMc group, 8 of 44 case recurred ang the rate was 18.2%. In THP group, 7 of 39 caes recurred and the rate was 17.9%. Conclusion To prevent postoperative recurrence of transitional cell carcinorma of bladder,there are no significat difference between MMe and THP intravesical instillation.
出处
《临床医学》
CAS
2009年第3期24-25,共2页
Clinical Medicine
关键词
膀胱移行细胞癌
丝裂霉素
吡柔比星
膀胱灌注
Transitional cell carcinorma of bladder
Mitomycin - C
Pirarubicin
intravesical instillation
