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Nodular liver lesions involving multiple myeloma: A case report and literature review 被引量:2

Nodular liver lesions involving multiple myeloma: A case report and literature review
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摘要 We report a case of a 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in a regular medical examination. Routine laboratory tests were normal. PET-CT showed multiple bone lesions and nodular liver lesions. Liver biopsy revealed nodular infiltration of multiple myeloma with positive staining of kappa light chain. Further investigation of bone marrow aspiration, immunofixation and immunoelectrophoresis of serum protein, urine test for Bence-Jones protein, 132-microglobulin in serum and urine confirmed the diagnosis. The patient also coinfected with hepatitis C virus (HCV). With six cycles of chemotherapy with VAD schedule, she achieved complete remission. In this report, a literature review of liver lesions involving multiple myeloma is also provided. We report a case of a 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in a regular medical examination. Routine laboratory tests were normal. PET-CT showed multiple bone lesions and nodular liver lesions. Liver biopsy revealed nodular infiltration of multiple myeloma with positive staining of kappa light chain. Further investigation of bone marrow aspiration, immunofixation and immunoelectrophoresis of serum protein, urine test for Bence-Jones protein, β2-microglobulin in serum and urine confirmed the diagnosis. The patient also coinfected with hepatitis C virus (HCV). With six cycles of chemotherapy with VAD schedule, she achieved complete remission. In this report, a literature review of liver lesions involving multiple myeloma is also provided.
机构地区 Liver Research Center
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第8期1014-1017,共4页 世界胃肠病学杂志(英文版)
关键词 Nodular lesions Liver Multiple myeloma IgA kappa light chain Hepatitis C virus 多发性骨髓瘤 结节性病变 文献复习 肝癌病灶 病例报告 多发性骨病变 丙型肝炎病毒 血清蛋白
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