2Giarre M,Caldeira S,Malanchi I,et al.Induction of pRb degradation by the human papillomavirus type16 E7 protein is essential to efficiently overcome P16INK4(A)-imposed G1 cell cycle arrest[J].J Virol,2001,75(10):4705-4712.
3Sherr C J.Cancer cell cycles[J].Science,1996,274(5293):1672-1680.
4Li Y,Nichols M A,Shay J W,et al.Transcriptional repression of the D-type cyclin dependent kinase inhibitor p16 by retinoblastoma susceptibility gene product pRb[J].Cancer Res,1994,54 (23):6078-6082.
5Sakaguchi M,Fujii Y,Hirabayashi H,et al.Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers:an immunohistochemical study[J].Int J Cancer,1996 65(4):442-445.
6Murphy N,Ring M,Killalea A G,et al.P16^INK4A as a marker for cervical dyskaryosis:CIN and cGIN in cervical biopsies and ThinPrep^TM smears[J].J Clin Pathol,2003,56(1):56-63.
7Steck P A,Pershouse M A,Jasser S A,et al.Identification of a candidate tumor suppressor gene,MMAC1,at chromosome 10q23.3 that is mutated in multiple advanced cancers[J].Nat Genet,1997,15(4):356-362.
8Pim D,Massimi P,Dilworth S M,et al.Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A[J].Oncogene,2005,24(53):7830-7838.
9Ansari-Lari M A,Staebler A,Zaino R J,et al.Distinction of endocervical and endometrial adenocarcinomas:immunohistochemical p16 expression correlated with human papillomavirus DNA detection[J].Am J Surg Pathol,2004,28(2):160-167.
10Clavel C,Masure M,Bory J P,et al.Hybrid Capture Ⅱ-based human papillomavirus detection,a sensitive test to routine high-grade cervical lesions:a preliminary study on 1518 women[J].Br J Cancer,1999,80(9):1306-1311.
