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HE4和CA125联合检测在卵巢癌手术前后临床价值评价 被引量:37

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摘要 目的探讨癌抗原125(CA125)、人附睾蛋白4(HE4)在卵巢癌诊断、治疗中的价值。方法测定122例女性血清CA125、HE4水平,其中体检健康女性46例作为正常对照组,盆腔肿物住院患者76例按术后病理结果分为良性病变组56例和卵巢癌组20例。卵巢癌组术后1个月再次复查CA125和HE4,观察术前术后指标变化。结果卵巢癌组CA125、HE4水平明显高于其他2组,差异有统计学意义(P<0.01),正常对照组和良性病变组比较差异无统计学意义(P>0.05)。卵巢癌组术后1个月复查CA125和HE4水平明显下降(P<0.05)。结论HE4联合CA125测定有助于卵巢良恶性肿瘤的鉴别诊断,是恶性肿瘤术后随诊监测的重要指标。
出处 《河北医药》 CAS 2009年第5期564-565,共2页 Hebei Medical Journal
基金 河北省科技厅科技研究与发展指导计划课题(编号:072761638)
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