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CEF方案新辅助化疗对乳腺癌组织BCSG1蛋白表达的影响

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摘要 采用免疫组化SP法分别检测102例行CEF联合方案新辅助化疗患者(新辅助化疗组)和同期110例未行新辅助化疗患者(对照组)手术切除的乳腺癌组织BCSG1蛋白的表达。同时对新辅助化疗组疗效进行病理形态学评价,并分析BCSG1蛋白表达与病理形态学变化的关系。结果发现新辅助化疗组BCSG1蛋白高表达率明显低于对照组(P<0.01),化疗后部分缓解(Ⅱ级)病例BCSG1蛋白高表达水平明显低于无效(Ⅲ级)病例(P=0.002)。认为采用CEF方案新辅助化疗近期疗效明显,可抑制乳腺癌BCSG1蛋白的表达。
出处 《山东医药》 CAS 北大核心 2009年第12期48-49,共2页 Shandong Medical Journal
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