摘要
目的评估中国部分城市中稳定期慢性阻塞性肺疾病(COPD)患者治疗用药状况。方法由中国呼吸病专家咨询小组设计调查方案,采取横断面调查,2006年7月至10月在中国6大城市对258名呼吸科医师和723例稳定期COPD患者进行面对面调查。医生方面调查包括:首诊及复诊COPD处方用药情况,对现有药物的评价,药物治疗对稳定期COPD的作用及对COPD患者治疗依从性的评价;患者方面包括用药情况、用药类别、用药过程如何调整剂量及停药情况。结果所用药物中(包括医生问卷及患者问卷回答)排在第一位是祛痰剂,其次是β2受体激动剂,M胆碱能受体拮抗剂排在第四位。82%医生认为大多数COPD患者治疗依从性较好,但是实际上大约50%患者会自行减少用药,尤其是一旦病情缓解就停止用药。结论COPD患者用药中,M胆碱受体拮抗剂应用不够普遍,相反祛痰药应用较多。COPD患者用药治疗依从性仍旧较差,需要大力加强COPD的教育和管理。
Objective To investigate and assess the condition of used medicine in the patiests with stable COPD in partial cities in China. Methods 723 stable COPD patiests and 258 physicians of respiratory department were interviewed faceto-face in outpatients＇ departments in 6 large cities in China. The questionnaire of physician included the condition of prescription medicine on initial and subsequent visit, their assessment of used medicine, effects of medicine on the patients with stable COPD, as well as the assessment of the patients＇ compliance, in addition, the condition used medicine, the kinds of used drugs, how to adjust the dose of drugs and the conditions of drug-withdraud reported by patients themselves. Results During the used medicine, including the answers of both physician, and patients, mucolytic agents ware arranged the first, next, ~_-agonists, and yet anticholinergics in the fourth,82 percent of physicians considered that the patiest with COPDhad betler compliance, but, in fact, aboat 50 percent of patieats changed their pharmacologic treatmeat plan, even stoped the medicine, once their ill condition was improved or relieved. Conclusion Antieholinergics was not used widespread in treatment of COPD patients, on the contrary, more mucolytic agents were used,Moreover,the patients＇eomplianee was relatively poor and needed to be improve.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2009年第4期354-357,共4页
Chinese Journal of Practical Internal Medicine
关键词
慢性阻塞性肺疾病
现况调查
β-受体拮抗剂
chronic obstructive pulmonary disease
stable stage
pharmacologic treatment
medicine
