摘要
目的探讨藤茶双氢杨梅树皮素(ampelopsin,APS)的抗肿瘤作用。方法以四甲基偶氮唑蓝比色法(MTT法)、克隆形成法观察APS对Hela细胞及A2780细胞的体外抑制作用。结果APS均能明显抑制体外培养的Hela细胞及A2780细胞的生长,MTT法的半数抑制浓度(IC50)分别为24.6μg/mL和1.2μg/mL,集落形成法中APS质量浓度在4.4～22.2μg/mL时抑制率均为100%。结论藤茶APS对体外培养的Hela细胞及A2780细胞均有明显的抑制作用。
Objective To investigate the anti- tumor effect of ampelopsin ampelopsin was analyzed by MTT and cell colony measurement. Results A2780 cells, IC50 was 24.6, 1.2 μg/mL in MTT assay. The repressive over 4.4-22.2 μg/mL. Conclusion Ampelopsin can inhibit the growth in vitro. Methods The growth inhibition in Hela, A2780 cells by Ampelopsin could obviously inhibit the growth of cultured Hela, ratio in cell colony assay was 100% when medicine density was of Hela, A2780 cells in vitro.
出处
《中国药业》
CAS
2009年第7期6-7,共2页
China Pharmaceuticals
基金
广西自然科学基金资助项目
项目编号:桂科基0639052
