摘要
目的探讨小剂量多巴胺联合溶栓治疗慢性肺栓塞并心功能不全的疗效。方法对我院2000~2008年4月,25例慢性肺栓塞并心功能不全患者应用小剂量多巴胺联合尿激酶溶栓,配合华法林、低分子肝素抗凝治疗,观察其水肿、血气分析、声心动图的变化。结果治疗后20例患者明显好转,有效率80%,PaO2上升差异有统计学意义(P<0.05),pH有所下降,PCO2有所上升,均无统计学意义(P>0.05),超声心动图右室舒张末径缩小、肺动脉压下降差异均有有统计学意义(P<0.05)。结论小剂量多巴胺联合溶栓治疗慢性肺栓塞并心功能不全疗效果显著,值得临床推广。
Objective Small dose of dopamine joint thrombolytic treatment of chronic pulmonary embolism and heart failure effect. Methods 2000~2008 in our hospital in April,25 patients with chronic pulmonary embolism and heart failure patients with lowdose dopamine joint urokinase,with warfarin,low-molecular-weight heparin anticoagulant therapy,observed edema,blood gas analysis,Echocardiography changes.Results After the treatment of 20 patients significantly improved,efficient 80%,PaO2 increase had a significant difference(P<0.05),pH has declined,PCO2 has increased,not statistically significant(P>0.05),cardiac ultrasound Figure dynamic right ventricular end-diastolic diameter narrowing,pulmonary artery pressure decreased differences were statistically significant(P<0.05).Conclusion Low-dose dopamine joint thrombolytic treatment of chronic heart failure and pulmonary embolism effect of fruit significantly,it is clinical.
出处
《中外医疗》
2009年第4期85-86,共2页
China & Foreign Medical Treatment
关键词
慢性肺栓塞
多巴胺
溶栓治疗
Chronic pulmonary embolism
Dopamine
Thrombolytic therapy