摘要
目的:观察在不同颅内压(ICP)压力水平时视觉诱发电位(VEP)和脑干听觉诱发电位(BAEP)的变化。方法:10只家免麻醉后建立急性颅内压增高的实验模型,用硬脑膜外纤维光束传感器测量不同阶梯ICP,同时观察VEP和BAEP的相应变化。结果:VEP的P_1、N_2波潜伏期延长与ICP增高均成正相关(r=0.62、r=0.60,P<0.01),其波幅的变化与ICP增高之间相关不良。BAEP的Ⅰ、Ⅲ、Ⅴ波潜伏期及Ⅰ~Ⅴ波峰间期与ICP增高之间无明显相关性。结论:VEP的P_1、N_2波潜伏期可用于无创伤监测ICP。
Objective: The relationship between intracranial pressure (ICP) and visual evoked potential (VEP) or brainstem auditory evoked potential(BAEP)was investigated. Method:An acute intracranial hypertension animal model was established in ten anesthetized rabbits. The changes of VEP and BAEP were observed by an AXON Systems Sentinel-4 Neurologid monitor at different levels of ICP,which were monitored with a fiberoptic transducer being inserted into the epidural space through a burrhole. Result:Both latencies of waves P_1 and N_2 of VEP was positively correlated with the ICP(r=0.62,r=0.60,P<0.01), but the amplitude of VEP was not well correlated with the ICP. However, the Ⅰ, Ⅱ and Ⅴ peak latency and the interval peak latency of Ⅰ and Ⅴ of BAEP were no relationship to the ICP. Conclusion:The latencies of wayes of P_1 and N_2 of VEP can be applied reliably to monitoring ICP noninvasively.
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
1998年第3期173-175,共3页
Chinese Journal of Anesthesiology
关键词
颅内压监测
视觉诱发电位
脑干
听觉诱发电位
Intracranial pressure Evoked potential, visual, auditory Monitoring, noninvasive