摘要
目的:了解氨基酮戊酸光动力疗法治疗尿道口尖锐湿疣的疗效和安全性。方法:213例尿道口尖锐湿疣患者采用5-氨基酮戊酸生理盐水溶液局部封包3 h后进行光动力学治疗,每周1次,最多治疗3次,疣体消退后再巩固治疗1次。结果:3次治疗后208例患者治愈,治愈率为97.7%。随访6个月,复发17例,复发率为8.2%。不良反应轻微。结论:氨基酮戊酸光动力疗法治疗尿道口尖锐湿疣疗效好,复发率低,不良反应少,是一种理想的治疗尿道口尖锐湿疣的方法。
Objectives： To investigate the clinical efficacy and safety of topical application of 5-aminolevulinic acid （ALA） photodynamic therapy （PDT） for the treatment of eondylomata aeuminata in urethral meatus. Methods： In total of 213 subjects were enrolled in the trail. The patients were treated with 20% ALA solution occlusive dressing for 3 h followed by irradiation with the helium-neon laser. The treatment was repeated 1 week later if the lesion was not completely removed after the first treatment. Once more therapy was carried out one week after the lesions were cleared. Results： Two hundred and eight sub- jects were cured after thrice therapies. The cure rate was 97.7% and the recurrence rate 8.2%. No severe adverse effect was found. Conclusion： Photodynamic therapy exhibits good efficacy and safety in the treatment of eondylomata acuminata in ure- thral meatus.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2009年第4期259-260,共2页
Journal of Clinical Dermatology
关键词
尖锐湿疣
5-氨基酮戊酸
光动力疗法
condylomata acuminate
5-aminolevulinic acid
photodynamic therapy
