摘要
对经颅磁刺激进行了磁场强度分布的测试,分为3个方面,即分别对经颅磁刺激轴向和径向磁场强度的分布及在有效刺激区内的磁场最强圆周上磁场强度分布矢量值进行测试。在对毒品依赖者的康复实验中,将经颅磁刺激具体应用到对毒品依赖者进行治疗的实验测试中。磁刺激前,要记录毒品依赖者的脑电图,同时给患者不同的毒品图片进行视觉刺激。随后进行1个疗程的经颅磁刺激。之后,再用与第1次相同的视觉刺激序列,给患者看与经颅磁刺激治疗前相同的毒品图片,并记录患者的脑电数据,将前后2次的脑电数据经过一定步骤的处理后,将得出的刺激前后的N270波幅和潜伏期数据进行比较分析。经颅磁刺激刺激后毒品依赖者的N270振幅会有明显的降低,潜伏期会缩短,并且吸毒患者异常脑区的脑功能有所变化。毒品依赖者大部分存在差异的电极位于人的大脑的额叶区、颞叶区、顶叶和枕叶区,因此可以预测其大脑的额叶、颞叶、顶叶和枕叶可能受到海洛因的损害,该区域脑功能异于正常人。经过1个疗程经颅磁刺激刺激后,毒品依赖者的N270振幅和潜伏期都更接近正常人。因此,经颅磁刺激治疗对于海洛因依赖者有一定的疗效。
The transcranial magnetic stimulation （TMS） we designed was first measured in terms of its magnetic field intensity distribution regarding three aspects, le. the distribution of magnetic field intensity in axial direction, in radial direction and around the circle which held the maximal magnetic field intensity. Then, it was applied into a therapeutic rehabilitation experiment of heroine addicts. Before TMS treatment, the electroencephalogram （EEG） results of patients, who were undergoing visual stimulation with different drug pictures, were recorded. These pictures were given to the patients after treatment once again in the same order, and then the EEG results were also recorded to make a comparison with the former ones. The two groups of data were processed in a certain procedure first, and then the obtained N270 amplitudes and latencies were compared and analyzed. The findings showed that the N270 amplitude of the drug addicts decreased after magnetic stimulation, and the latency was shortened. There were also brain functional changes in the abnormal encephalic regions. And it was in the frontal lobe, the temporal lobe, the temporal lobe and the occipital lobe region where most differential electrodes appeared. We concluded accordingly that all of these above-mentioned brain regions of the patients were possibly injured by heroin and functions of these parts were abnormal. However, through a course of TMS treatment, the N270 amplitude and latency got closer to the normal value, which suggests that the TMS contributes to the recovery of heroin addiction.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2009年第13期2443-2446,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
