摘要
目的:评价氨酚羟考酮片治疗中重度腰腿痛的疗效和安全性。方法:将76例中重度腰腿痛患者随机分为治疗组和对照组,每组均为38例。治疗组给予口服氨酚羟考酮片,对照组给予布洛芬缓释胶囊治疗。结果:对总体疗效而言,两组总有效率分别为91.18%和80.00%,总体疗效及改善重度疼痛患者VAS评分等的差异有统计学意义(P<0.05)。临床观察中未发现氨酚羟考酮片有何明显的毒副作用和不良反应。结论:氨酚羟考酮片治疗中重度腰腿痛安全有效,值得在临床上推广应用。
Objective： To assess the efficacy and safety of oxycodone-acetaminophen tablet（Tylox） in the treatment of moderate or severe lumbocrural pain.Methods： Patients with moderate or severe lumbocrural pain（n=76） were randomly divided into 2 groups,and treated with oxycodone-acetaminophen（n=38） or ibuprofen sustained release capsules（n=38,control）.The symptoms were observed to evaluate their effects 7 days after the treatments.Results： The overall effective rate was 91.18% in Tylox group or 80.00% in the control group,there was a significant difference between two groups（P〈0.05）.No apparent adverse effect was found during the observation period.Conclusion： The oxycodone-acetaminophen tablet is effective and safe in the treatment of moderate or severe lumbocrural pain.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2009年第5期420-423,共4页
Chinese Journal of New Drugs
关键词
氨酚羟考酮片
腰腿痛
疗效
oxycodone-aeetaminophen tablet
lumbocrural pain
efficacy
