摘要
目的:探讨糖皮质激素在早产治疗中的作用和合理应用。方法:回顾性分析2002年1月～2008年7月112例早产患者的临床资料,80例患者产前应用地塞米松组和32例早产患者未用地塞米松组早产儿的结局情况。结果:孕28～34周分娩者79例,其中应用地塞米松组65例,早产儿窒息4例(6.15%);未用地塞米松组14例,早产儿窒息4例(28.57%);两组患者早产儿结局比较差异有统计学意义(P<0.05),应用地塞米松组新生儿窒息发生率明显降低。孕34～37周分娩者33例,其中应用地塞米松组15例,早产儿窒息2例(13.3%);未用地塞米松组18例,早产儿窒息3例(16.67%)。两组患者早产儿结局比较差异无统计学意义(P>0.05)。结论:对孕34周以前,不可避免发生早产且临床无感染征象者,产前应用糖皮质激素可明显降低早产儿的NRDS发生率。
Objective： To explore the function and valid usage of corticotrophin in the treatment of premature delivery. Methods： Clinical data of 112 cases with premature delivery during January 2002 to July 2008 were analyzed retrospectively, and the outcomes of 80 cases treated by corticotrophin and 32 cases without corticotrophin treatment were. compared. Results ： Among 79 cases premature delivery during 28 -34 gestational weeks, 65 cases were treated by corticotrophin and 4 cases were found asphyxia （6. 15% ）, 14 cases didnt receive corticotrophin and 4 cases were found asphyxia （28. 57% ）, the incidence of asphyxia had difference （P 〈 0. 05 ） . Among 33 cases premature delivery during 34 - 37 gestational weeks, 15 cases were treated by eorticotrophin and 2 cases were found asphyxia （ 13.3% ）, 18 cases didn＇t receive corticotrophin and 3 cases were found asphyxia （ 16. 67% ）, the incidence of asphyxia had no difference （ P 〉 0.05 ）. Conclusion： Corticotrophin plays an important rolr in the inevitable preterm delivery before 34 gestational weeks without infection.
出处
《中国妇幼保健》
CAS
北大核心
2009年第11期1479-1480,共2页
Maternal and Child Health Care of China
关键词
糖皮质激素
早产
早产儿
Corticotrophin
Premature delivery
Premature infant
