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Synthetic Studies of an Analogue of HIV-1 Protease Inhibitors of Didemnaketals:Construction of the C1-C8 Intermediate

Synthetic Studies of an Analogue of HIV-1 Protease Inhibitors of Didemnaketals:Construction of the C1-C8 Intermediate
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摘要 A convenient and stereoselective approach to the synthesis of(3S. 4R. 6S)- 2-oxo-3, 4-dihydroxy-6-methyl-octanate derivative, a key intermediate for the synthesis of HIV-1 protease inhibitor of didemnaketals analogue, has been developed successfully from L-(-)-menthone. A convenient and stereoselective approach to the synthesis of(3S. 4R. 6S)- 2-oxo-3, 4-dihydroxy-6-methyl-octanate derivative, a key intermediate for the synthesis of HIV-1 protease inhibitor of didemnaketals analogue, has been developed successfully from L-(-)-menthone.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第9期749-750,共2页 中国化学快报(英文版)
关键词 didemnaketals 2-oxo-3 4-dihydroxy-6-methyl-octanate steroselective synthesis didemnaketals 2-oxo-3 4-dihydroxy-6-methyl-octanate steroselective synthesis
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