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Synthesis and Antitumor Activity of4β-(1,2,3-Triazol-1-yl) podophyllotoxins 被引量:3

Synthesis and Antitumor Activity of 4β-(1,2,3-Triazol-1-yl) podophyllotoxins
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摘要 Three 4β-(1,2,3-triazol-1-yl) podophyllotoxins 2~4 have been synthesized and testedtar their antitumor activity in vitro. The compound 3 was found to be much more cytotoxic than theclinically used etoposide (VP-16) against L 1210 cells. Three 4β-(1,2,3-triazol-1-yl) podophyllotoxins 2~4 have been synthesized and testedtar their antitumor activity in vitro. The compound 3 was found to be much more cytotoxic than theclinically used etoposide (VP-16) against L 1210 cells.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第12期0-0,0-0,共4页 中国化学快报(英文版)
关键词 Podophyllotoxin ANTITUMOR synthesis. Podophyllotoxin, antitumor, synthesis.
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