摘要
本文通过对35例非胰岛素依赖型糖尿病患者外周血红细胞膜胰岛素受体数(EIR)及糖化血红蛋白(HbAic)的测定,发现两参数之间的相关系数r=-0.694(P<0.01);而两种不同亲和力的胰岛素受体数之比(高亲和力结合位点数/低亲和力结合位点数)与HbAic的相关系数r’=-0.001(P>0.05).作者认为细胞膜上胰岛素受体绝对数目的变化在血红蛋白糖基化过程中与精化的产物HbAic呈负相关,而两种不同亲和力受体数目之比值则与HbAic无明显相关性.
We determined the insulin receptor of erythrocyte membrane in circulating blood and HbAIc in 35 cases of NIDDM, and found that the correlate coefficient of the two biochemistry indexes was r=-0. 694 (P<0. 01); but there was no correlation between the HbAIc and the ratio of high affinity receptor numbers to low affinity receptor numbers (r' = -0. 001,P>0. 05). The result indicated that changes of insulin receptor numbers was inversely correlated with HbAIc and the ratio of high and low affinity receptor numbers was not significantly related to HbAIc.
出处
《山西职工医学院学报》
CAS
1995年第2期1-2,共2页
Journal of Shanxi Medical College for Continuing Education
