摘要
目的：评价生脉注射液治疗心绞痛患者的疗效。方法：观察了２４８例心绞痛患者采用生脉注射液治疗前后血液粘度、左心室功能和心电图的变化，并用丹参注射液治疗４４例作对照。结果：生脉注射液对改善心电图的有效率（７１．２％）好于丹参注射液（６０．０％），但Ｐ＞０．０５；生脉注射液可明显增加心搏出量，降低外周血管阻力，改善左心室功能；生脉注射液和丹参注射液都明显降低血液粘度。结论：与丹参注射液比较，生脉注射液改善心绞痛患者心功能的效果较好；生脉注射液增加心脏每搏输出量（ＳＶ），每分输出量（ＣＯ）和心脏指数（ＣＩ），降低外周血管阻力（ＳＶＲ）可能与其清除自由基有关。
Objective:To evaluate the therapeutic efficacy of “sheng mai” injection treating angina pectoris (AP).Methods:Two hundred and fortyeight cases of AP were treated with “sheng mai” injection.Then,to observe the changes of blood viscosity,left ventricular function and electrocardiogram (ECG) before and after therapy.In addition,fortyfour patients were treated with “dan shen” injection(丹参注射液) as control group.Results:The “sheng mai” injection raised cardiac output obviously,decreased perivascular resistance and improved left ventricular function.The effective rate of ECG improvement induced by “sheng mai” injection was 712%,it was superior to “dan shen” injection (600%).but P>005.Both “sheng mai” and “dan shen” injection could decrease blood viscosity obviously.Conclusions:The effectiveness of “sheng mai” injection is better than “dan shen” injection for improving cardiac performance in patients with AP.“Sheng mai” injection can raise cardiac stroke and cardiac output,decrease perivascular resistance.It may relate to removing free radical.
关键词
生脉注射液
血液粘度
心功能
丹参注射液
心绞痛
“sheng mai” injection blood viscosity cardiac performance “dan shen” injection
