摘要
目的：观察联合应用生脉注射液及巯甲丙脯酸治疗充血性心力衰竭（ＣＨＦ）的疗效。方法：随机将资料完整的ＣＨＦ患者１００例分为治疗组和对照组各５０例，２组均在原发病治疗基础上，继续应用洋地黄及襻利尿剂；治疗组加用生脉注射液６０ｍｌ加５％葡萄糖２００ｍｌ静滴，每日１次；口服巯甲丙脯酸２５ｍｇ，每日３次，１４日为１个疗程。结果：治疗组总有效率８８．０％，对照组总有效率６４．０％，２组比较有显著性差异（Ｐ＜０．０５）。结论：生脉注射液能增强左室收缩力，增加心输出量及减慢心率；巯甲丙脯酸能使周围动脉扩张，亦有扩张静脉作用，从而降低心脏前后负荷，增加心排血量。２药合用治疗ＣＨＦ疗效较好，无明显副作用，值得推广。
Objective:To observe the therapeutic efficacy of “sheng mai” injection combined use of captopril in treating congestive heart failure (CHF).Methods:One hundred cases of CHF were divided randomly into treatment group (n=50) and control group (n=50).The treatment group was treated with “sheng mai” injection 60 ml in 5% glucose 200 ml for intravenous drip,once every day,and oral captopril 25 mg,3 times every day basis on treated with digitalis and uretic drug continously.The control group was treated with digitalis and uretic drug basis on conventional therapy.Results:The total effective rates were 880% and 640% in treatment group and control group respectively.There was obvious difference between 2 groups (P<005).Conclusions:“Sheng mai” injection can enbance left ventricular contractility,raise cardiac output and decrease heart rate.Captopril can dilate periartery and vena.Therefore,it can increase the cardiac output through decreasing preload and afterload.
