摘要
对32例ENL患者血清中的PG-Ⅰ抗体和CIC水平作了检测,并与56例无ENL的麻风患者作对照。结果显示ENL患者血清中抗PG-Ⅰ抗体及CIC的水平与无ENL的两组麻风患者相比有显著差异(P<0.05),其特征是随ENL的出现血清中抗PG-Ⅰ抗体水平下降,CIC水平上升。ENL治愈后,PG-Ⅰ抗体及CIC水平逐渐恢复到反应前水平。著者认为血清抗PG-Ⅰ抗体及CIC水平的变化对促发ENL有一定作用,但强调这还不能完全解释ENL的发病机制问题,尚应作系统深入的研究。
The examination of anti-PG1 antibody and immunocomplexes in the sera of 32 leprosy patients with ENL and of 56 cases without ENL shown a significant difference (P<0.05) , i. e. in the former the level of the antibody decreased and that of the immunocomplex increased. After cure of ENL, the levels were restored to those before ENL.The authors point out that the changes in contents of antibody and immunocomplex in the sera of leprosy patients have some effect on the occurence of ENL, but still can not explain its pathogenesis.
出处
《中国麻风皮肤病杂志》
北大核心
1990年第1期18-21,共4页
China Journal of Leprosy and Skin Diseases