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冠心病患者Holter监测暂短性ST段压低的预后意义

PROGNOSTIC SIGNIFICANCE OF TRANSIENT ST-SEGMENT DEPRESSION IN CORONARY HEART DISEASE PATIENTS BY HOLTER MONITORING
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摘要 本文对144例动态心电图检出的暂短性ST段压低(TSTD)的冠心病(CHD)患者随访1.5~3.5年(平均2.7年),并与149例同期监测无TSTD的CHD患者进行对照。前者的平均年龄小,病程短,但陈旧性心肌梗塞例数多,心性病死率高。在TSTD组中,与死亡者相比,随访期间存活者的心功能指标(SV、CI及PEP/LVET)较为优越,平均室早计数较少,TSTD频度低且持续时间较短。 Many recent studies described transient ST-segment depression (TSTD) during daily activities using Halter monitoring. However, the prognostic significance of TSTD have not yet been studied. In this study, 293 cases with coronary heart disease (CHD), with or without TSTD recorded on 24 hour Halter during daily activities, were divided into two groups: TSTD group (144 eases, TG) and non-TSTD group (149 cases, NTG). Patients with acute or recent myocardial infarction, unstable angina and serious heart failure were excluded. All patients were followed-up for 1.5 to 3.5 years (mean 2.7 years) and the results were compared. Average age and CHD natural history in TG (58.3±21.6 years and 5.64±1.9 years) were significantly lower than those of NTG (63.7±18.2 years and 8.1±2.1 years; P<0.02 and P<0.05 respectively), but the prevalence of old myocardial infarction and incidence of cardiac death in the former (57 cases and 13 cases) were higher than those in tha latter(16 cases and 3 cases; P<0.001 and P<0.05 respectively). During the followed-up period, cardiac function (SV, CI and PEP/LVET) in the living TC were significantly better, as compared to the dead TC. Average number of ventrieular premature beats in the living TG was 182±51 beats/day vs 439±211 beats/day in the dead TG(P<0.05). Avreage number of TSTD episodes in the living TG was 10±5 times/day vs 20±11 times/day in the dead TG (P<0.01). Averags total TSTD period in the living was 39.8±27.6 min/day vs 51.4±38.8 in the dead (P<0.05). Thus among patients with CHD, TSTD on Holter monitoring are a strong predictor of cardiac events.
出处 《中国循环杂志》 CSCD 1990年第6期437-439,508-509,共5页 Chinese Circulation Journal
关键词 冠心病 HOLTER监测 暂短性心肌缺血 Coronary heart disease Holter monltoring Transient myocardial ischemia
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参考文献8

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