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益智仁药理作用的初步研究 被引量:6

PHARMACOLOGICAL STUDY OF FRUCTUS ALPINIAE OXYPYLLAE
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摘要 益智仁氯仿提取物和益智仁水提物具有中枢抑制作用,均能明显提高戊巴比妥纳阈下剂量的小白鼠的睡眠率。具有镇痛作用和提高小白鼠常压下耐缺氧存活时间。益智仁氯仿提取物能提高异丙肾上腺素作用下的小白鼠常压下耐缺氧存活时间。二种提取物均能使幼年大白鼠脾脏、胸腺缩小。 Two extractions from Fructus Alpiniae Oxypyllae with chloroform (A) and water(B) showed central depression effect, and obviously enhanced the asleep rate of mice, received subthreshold dose of sodium pentobarbital. Both extractions had an analgesic effect and can prolong the survival time of the mice under hypoxia and normal pressure, but only the extraction of chloroform (A) can enhance the survival time of the mice, received isoprenaline. Both extractions re- duced the weight of spleen, thymus, and quantity of vitamin C within the adrenal of the seedling rats.
出处 《广东药学院学报》 CAS 1989年第2期48-52,共5页 Academic Journal of Guangdong College of Pharmacy
关键词 益智仁 中枢抑制 镇痛 耐缺氧 垂体一肾上腺皮质系统 Fructus Alpiniae Oxypyllae central depression effect analgesia under hypoxia pituitary-adrenocortical system
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