摘要
With regard to brain acetylcholinesterase and acetylcholine and serum triiodothyronine（T<sub>3</sub>）and thyroxine（T<sub>4</sub>）profiles,a biphasic response pattern was elicited in Channa punctatus chroni-cally exposed to nonlethal doses of locally used pesticides,namely,Metacid-50 and Carbaryl.Data revealed that these xenobiotics caused significant inhibition of brain acetylcholinesteraseactivity and a decrease in thyroxine level accompanied by a concurrent increase in acetylcholineaccumulation and T<sub>3</sub> level.It is surmised that Metacid-50 and Carbaryl influence both neuraland hormonal functions.1989 Academic Press.Inc.
With regard to brain acetylcholinesterase and acetylcholine and serum triiodothyronine(T_3) and thyroxine(T_4)profiles,a biphasic response pattern was elicited in Channa punctatus chroni- cally exposed to nonlethal doses of locally used pesticides,namely,Metacid-50 and Carbaryl. Data revealed that these xenobiotics caused significant inhibition of brain acetylcholinesterase activity and a decrease in thyroxine level accompanied by a concurrent increase in acetylcholine accumulation and T_3 level.It is surmised that Metacid-50 and Carbaryl influence both neural and hormonal functions.1989 Academic Press.Inc.
