摘要
本文着重介绍了采用作者建立的一种灵敏的放射免疫方法,测定老年心血管、脑疾病中血浆ANP含量。晚期肺心病老年患者,血浆ANP含量明显低于早期PHD者(P<0.05)。伴有左心室肥厚的高血压老年患者血浆ANP浓度明显高于左心室正常的高血压患者(P<0.01)。高血压脑卒中后血压仍高和血压正常的老年患者,血浆ANP分别为861.1±108.4和536.8±50.1pg/ml。总之,测定老年人血浆ANP的浓度,对于探讨老年人心血管、脑血管疾病的发病机理和病情严重程度有重要意义。
This article mainly reportes the procedure by which the plasma ANP levels in elderly patients with cardiovascular and cerebral diseases, using a sensitive RIA devloped in our laboratory.The plasma ANP levels in patients with advanced stage PHD were significantly lower than those with early stage PHD (P<0.05). The ANP values of plasma in 14 with LVH are significantly higher than those in 16 with normal size left ventricle (p<0.01). The ANP concentritions of plasma of patients with cerebral stroke in the presene of hypertension are 861.1 ±108.4 in pafients with higher BP and 536.8±50.2 in pafients with normal BP.In summary, determination of plasma ANP levels in the eldery patients plays an important role in understanding the mechanism and severity of cardiovascular and cerebral diseases.
出处
《解放军医学院学报》
CAS
1989年第3期206-208,共3页
Academic Journal of Chinese PLA Medical School
关键词
脑血管意外
心力衰竭
充血性
高血压
放射免疫测定
Cerebrovascular disorlers Heart failure
congestive Hypertension Radioimmunoasssay
