摘要
目的探讨联合检测丙型肝炎抗体和核心总抗原（HCV—cAg）在临床中的应用价值。方法用酶联免疫吸附试验（ELISA）法联合检测HCV抗体和HCV—cAg，并与荧光定量PCR法检测丙型肝炎核酸（HCV—RNA）的结果进行对照。结果157例患者中共检出HCV抗体阳性149例、HCV—cAg阳性99例、HCV-RNA阳性115例；5例HCV抗体阴性而HCV—cAg阳性的患者，经HCV—RNA证实为HCV感染；共检出HCV抗体或HCV—cAg阳性154例，另外3例经HCV—RNA排除HCV感染。结论联合检测HCV抗体和HCV—cAg提高了HCV感染的检出效率，可有效避免漏检，适合在普通医疗机构推广使用。
Objective To discuss the clinical application value of combined detection of hepatitis C virus antibody and core antigen （HCV-cAg）. Methods Serum sample were combined tested for HCV antibody and HCV- cAg by enzyme-linkod immnosorbent assy（ELlSA） kit, then the results were compared with those detected by fluorescent quantitation PCR for hepatitis C virus ribonueleie acid（HCV-RNA）. Results Among the 157 patients, 149 were positive for HCV-Ab, 99 positive for HCV-cAg and 115 for HCV-HNA. Respectively： 5 patients who were negative for HCV antibody and positive for HCV-eAg were confirmed to be HCV infection by HCV-RNA. 154 patients were positive for HCV antibody or HCV-eAg, the other 3 were excluded from HCV infection. Conclusion Combined detection of HCV antibody and HCV-cAg can improve the detection rate of HCV infection, avoid omission effectively, and is suitable for promotion in common medical institutions.
出处
《国际医药卫生导报》
2009年第8期77-79,共3页
International Medicine and Health Guidance News
