摘要
目的探讨鲎试验检测方法在输液反应中应用的效果。方法利用鲎试验与细菌内毒素产生凝集反应的机制,以判断供试品中细菌内毒素的限量是否符合规定的一种方法。结果对23例输液反应进行鲎试验检查结果进行分析,其主要原因有液体制备过程热原超标,联合用药配伍不当,添加药物过多或添加药物本身热原不合格;输液器具、治疗室空气污染;操作时违犯无菌技术操作规程;药物配制太久,输液时间过长和输液速度过快等。结论输液反应的预防应从各环节抓起,严格执行各项无菌操作技术,提倡单剂量输液,杜绝或减少输液反应。
OBJECTIVE To discuss the application of tachypleus amebocyte lysate test in transfusion reaction. METHODS Based on agglutination when tachypleus amebocyte lysate test encountered bacterial endotoxin, the quantity of the bacterial endotoxin was tested. RESULTS Twenty-three cases were analyzed with tachypleus ameboeyte lysate test, the main reasons were excessive pyrogen, improper combined drug compatibility, excessive agents or unqualified pyrogen of the agent added, pollutions on transfusion devices and air in the treatment room, disobeying axenic operation rules, overlong drug dispensing, too fast transfusion speed, etc. CONCLUSIONS On prevention of transfusion reaction, all the axenic operation rules should be strictly followed, single dose transfusion, to reduce transfusion reaction.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2009年第8期947-948,共2页
Chinese Journal of Nosocomiology
关键词
鲎试验
热原
输液反应
Tachypleus amebocyte lysate test
Pyrogen
Transfusional reaction
