摘要
目的探讨经蝶窦入路治疗垂体腺瘤的临床意义。方法2001年9月～2008年3月共选择收治垂体腺瘤患者134例,术前均进行冠状CT、MRI检查,并行内分泌学检查。均行单鼻孔蝶窦入路显微手术治疗。术后随访6～36个月。结果肿瘤全切107例,次全切21例,部分切除6例。术后症状及内分泌检查改善122例,41例出现一过性尿崩,10例出现并发症,包括鼻中隔穿孔,鼻黏膜感染,脑脊液漏。5例1年后复发。结论经蝶窦手术治疗垂体腺瘤创伤小,操作简单,安全,肿瘤切除完全,住院时间短,费用低。
Objective To explore the clinical significance of resection of pituitary adenomas via endonasal trans-sphenoidal sinus approach. Methods 134 patients with pituitary adenoma were treated by resection via endonasal trans-sphenoidal sinus approach from September 2001 to March 2008. All the patients received coronal CT and MRI scan, and endocrinological examinations before operation and followed up for 6 - 36 months after operation. Resulta The tumors were removed totally in 107 patients, sub-totally in 21 patients, and partially in 6 patients. 122 patients achieved an improvement in clinical and endocrinologieal examinations. Postoperative complications were found in 10 patients, including nasal septum perforation, nasal mucosal infection and cerebrospinal rhinorrhea. 5 patients relapsed 1 year after operation. Conclusion The resection of pituitary adenomas via endonasal trans-sphenoidal sinus approach is minimal invasive, simple and safe, with low cost and relatively high total resection rate, and shorter hospital stay.
出处
《云南医药》
CAS
2009年第2期129-132,共4页
Medicine and Pharmacy of Yunnan
关键词
垂体瘤
单鼻孔
经蝶窦入路
显微手术
Pituitary adenoma
Endonasal trans-sphenoidal sinus approach
Microsurgery
