摘要
目的对４７例慢性乙型肝炎、肝炎肝硬化与散发性戊型肝炎重叠感染及５０例慢性乙肝进行临床对比分析，以探讨双重感染的临床特征、重症肝炎发生率及转归。方法采用ＥＬＩＳＡ法及ＥＩＡ法检测甲乙丙丁戊与５种肝炎病毒，同时检测肝功能（ＳＢ、ＡＬＴ、ＡＳＴ、Ａ／Ｇ、ＰＴ）。结果在ＨＢＶ感染的基础上重叠ＨＥＶ感染时，临床症状加重，深度黄疸的发生率高，血清白蛋白减低明显，凝血酶原时间明显延长，病情恢复慢，重症肝炎发生率高，病死率亦高。结论提示ＨＢＶ与ＨＥＶ重叠感染肝细胞损害加重，病情有重症化倾向。
bjective In order to determine the characteristic of superinfection of chronic hepatitis B,hepatitis hepatocirrhosis and virus hepatitis E on clinical aspects,case fatality rate and prognosis.Methods The ELISA,EIA thchniques were used to detect the serotogic markers of 5 kinds of hepatitis viruses-HAV,HBV,HCV,HDV,HEV.and liver function (SB,ALT,AST,A/G PT) were detected in 97 patients with chronicliver disease.Results The results showed that clinical symptom may be more severe when caused by superinfection chronic HB and HE than by chionic HB.It can be seen that serious icterus appears easilier,seralbumin obviously going down,time of prothrombuse prolonged and patients recovering slowly,which is liable to lead to necrotic hepatitis and high mortality.Conclusions dual infection of HBV and HEV may increase the incidence of necrotic hepatitis,which may exacerbate liver cells damage
出处
《宁夏医学杂志》
CAS
1998年第2期82-83,共2页
Ningxia Medical Journal
