摘要
目的探讨克罗恩病的诊断及治疗方法。方法回顾性分析13年间经病理确诊为克罗恩病30例的临床资料。26例获随访。结果30例患者,经手术病理诊断17例(56.7%),结肠镜活检诊断13例(43.3%)。17例手术患者中,术前诊断急腹症6例,肠梗阻4例,消化道大出血3例,结肠癌2例,胰头占位病变1例,肠瘘1例。随访26例患者中,15例接受过外科治疗,复发5例,21例有服用药物治疗史,治疗总有效率73.1%。近1个月病情缓解患者13例(13/23,56.5%)。结论克罗恩病病情迁延,诊断困难,多因误诊或并发症手术,术后易复发,生活质量低,应对该类患者提高警惕,以早期诊断,并加强随访和指导治疗。
Objective To investigate the diagnosis and therapy of Crohn＇s disease （CD）. Methods The clinical data of 30 cases of pathologically proven CD from 1992 to 2005 were analyzed, 26 cases were followed up. Results Among the 30 patients with CD, 13 （43.3 % ） diagmosed by endoscopy and biopsy. and 17 cases （ 57.7 % ） were diagnosed by operation and pathology Before operation, 6 cases were diagnosed as acute abdomen, 4 cases as ileus, 3 cases as massive hemorrhage of gastrointestinal tract, 2 cases as colorectal cancer, 1 case as intestinal fistula and 1 case as head mass of pancreas. Of the 26 cases followed up eases, 15 cases accepted operation with 5 cases of recurrence; 21 cases have taken drugs, and the total effective rate was 73. 1%. Conclusions CD is a chronic relapsing disease and is difficult to diagnose. The majority of patients undergo operation due to misdiagnosis or complications. CD is prone to relapse postoperatively, quality of life is poor, and one must heighten awareness of these patients, make early diagnosis, directed therapy, and intensify follow up.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2009年第4期379-382,共4页
China Journal of General Surgery
