摘要
目的:对57例IgA肾病患者中医虚证证候进行了辨证分型的临床相关性研究。方法:调查IgA肾病患者57例,对症状、临床指标及病理改变进行评分,统计其出现的频率和积分,采用统计软件SPSS进行比较分析研究。结果:虚证证型分布以气阴两虚最为多见;血尿多见于阴虚及气阴两虚型;低蛋白血症的发生及24h尿蛋白定量偏多与脾肾气虚型密切相关;高血压发生率肝肾阴虚组明显高于脾肾气虚组及气阴两虚组;病理损害程度肝肾阴虚组最轻,明显低于脾肾气虚组及气阴两虚组(P<0.05)。结论:IgA肾病中医虚证的3种主要证型其临床指标和病理改变有显著差异。
Objective： To make the related clinical research on syndrome differentiation in TCM deficiency-syndrome of 57 cases with IgA nephropathy. Methods： To investigate 57 patients of IgA nephropathy,we give the scores of symptoms,clinical indexes and pathological changes.Then we add up the frequency and integration and compare and analyze the results using SPSS statistical software. Results： The distribution of deficiency-syndrome types shows that qi and yin deficiency syndrome is the most type. Hematuria is often seen in yin deficiency syndrome and qi and yin deficiency syndrome. The occurrence of hypoproteinemia and 24h urinary protein excretion are closely related to spleen-kidney qi deficiency syndrome. The incidence rate of hypertension is higher in liver-kidney yin deficiency syndrome than in spleen-kidney qi deficiency syndrome and qi and yin deficiency syndrome. Pathological damage is the lowest in liver-kidney yin deficiency syndrome, and it is obviously lower than spleen-kidney qi deficiency syndrome and qi and yin deficiency syndrome （P〈0.05）. Conclusion： There were significant differences of clinical indexes and pathological changes between three types of TCM deficiency-syndrome of IgA nephropathy.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2009年第5期673-676,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
IGA肾病
中医虚证
病理改变
IgA nephropathy
TCM deficiency-syndrome
pathological changes
