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睾酮与代谢综合征及勃起功能障碍关系的研究新进展 被引量：4

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摘要 代谢综合征、性腺功能低下和勃起功能障碍常同时伴行、相互促进,严重影响中老年男性的生活质量,对三者之间内在联系的研究日益引起国内外学者的广泛关注。该文就近年有关研究的最新成果作一综述,供临床参考。
作者 徐和平 田二坡
机构地区 南昌市男科医院性功能康复科
出处 《新医学》 2009年第5期343-345,共3页 Journal of New Medicine
关键词 代谢综合征 睾酮 勃起功能障碍 男性
分类号 R589 [医药卫生—内分泌] R698 [医药卫生—泌尿科学]
  • 相关文献

参考文献15

  • 1YASSIN A A, SAAD F, GOOREN L J. Metabolic syndrome, testosterone deficiency and erectile dysfunction never come alone [ J ]. Andrologia, 2008, 40 (4) : 259 -264.
  • 2Norman C.W.WONG,肖海鹏.中国人的代谢综合征研究展望(英文)[J].中山大学学报（医学科学版）,2005,26(1):1-3. 被引量：3
  • 3李树彬,ADH IKARICM,高修仁.炎症、炎症介质和代谢综合征[J].新医学,2006,37(2):131-134. 被引量：24
  • 4JONES R D, NETTLESHIP J E, KAPOOR D, et al. Testosterone and atherosclerosis in aging men: purported association and clinical implications [J]. Am J Cardiovasc Drugs, 2005, 5 (3): 141-154.
  • 5SHABSIGH R, RAJFER J, AVERSA A, et al. The evolving role of testosterone in the treatment of erectile dysfunction [ J J. Int J Clin Pract, 2006, 60 ( 9 ) : 1087-1092.
  • 6MAKINEN J, JARVISALO M J, POLLANEN P, et al. Increased carotid atherosclerosis in andropausal middle-aged men [ J ]. J Am Coll Cardiol, 2005, 45(10) : 1603-1608.
  • 7SAAD F, GOOREN L J, HAIDER A, et al. A dose-response study of testosterone on sexual dysfunction and features of the metabolic syndrome using testosterone gel and parenteral testosterone undecanoate [ J ]. J Androl, 2008, 29 (1) : 102-105.
  • 8ALLAN C A, STRAUSS B J, BURGER H G, et al. Testosterone therapy prevents gain in visceral adipose tissue and loss of skeletal muscle in nonobese aging men[J]. J Clin Endocrinol Metab, 2008, 93(1) : 139-146.
  • 9PAGE S T, AMORY J K, BOWMAN F D, et al. Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T [ J ]. J Clin Endocrinol Metab, 2005, 90 (3): 1502-1510.
  • 10SELVIN E, FEINLEIB M, ZHANG L, et al. Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES Ⅲ) [J]. Diabetes Care, 2007, 30 (2): 234-238.

二级参考文献32

  • 1中华医学会糖尿病学分会代谢综合征研究协作组.中华医学会糖尿病学分会关于代谢综合征的建议[J].中国糖尿病杂志,2004,12(3):156-161. 被引量：3059
  • 2WELLEN K E,HOTAMISLIGIL G S.Obesity-induced inflammatory changes in adipose tissue[J].J Clin Invest,2003,112 (12):1785-1788.
  • 3DANDONA P,ALJADA A,MOHANTY P,et al.Insulin inhibits intranuclear nuclear factor kappa B and stimulates I-kappa B in mononuclear cells in obese subjects:evidence for an anti-inflammatory effect[J]? J Clin Endocrinol Metab,2001,86 (12):3257-3265.
  • 4ALJADA A,GHANIM H,MOHANTY P,et al.Insulin inhibits the proinflammatory transcription factor early growth response gene-1 (Egr) -1 expression in mononuclear cells (MNC) and reduces plasma tissue factor(TF) and plasminogen activator inhibitor-1 (PAI-l) concentrations[J].J Clin Endocrinol Metab,2002,87 (3):1419-1422.
  • 5TAKEBAYASHI K,ASO Y,INUKAI T.Initiation of insulin therapy reduces serum concentrations of high-sensitivity C-reactive protein in patients with type2 diabetes[J].Metabolism,2004,53 (6):693-699.
  • 6STENTZ FB,UMPIERREZ GE,CUERVO R,et al.Proinflammatory cytokines,markers of cardiovascular risks,oxidative stress,and lipid petoxidation in patients with hyperglycemic crises[J].Diabetes,2004,53(8):2079-2086.
  • 7JESCHKE M G,KLEIN D,BOLDER U,et al.Insulin attenuates the systemic inflammatory response in endotoxemic rats[J].Endocrinology,2004,145 (9):4084-4093.
  • 8JESCHKE M G,EINSPANIER R,KLEIN D,et al.Insulin attenuates the systemic inflammatory response to thermal trauma[J].Mol Med,2002,8 (8):443-450.
  • 9HOTAMISLIGIL G S.Inflammatory pathways and insulin action[J].Int J Obes Relat Metab Disord,2003,27 (Suppl 3):S53-S55.
  • 10SENN J J,KLOVER P J,NOWAK I A,et al.Suppressor of cytokine signaling-3 (SOCS-3),a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes[J].J Biol Chem,2003,278 (16):13740-13746.

共引文献25

同被引文献16

引证文献4

二级引证文献6

新医学
2009年 第5期

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