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血清IgA及IgA/C3比值在IgA肾病诊断中的价值 被引量:8

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摘要 IgA肾病(IgA nephropathy,IgAN)是我国最常见的原发性肾小球肾炎、但至今其确切发病机制仍不明确。免疫反应和补体系统可能在IgAN的发生、发展中起重要作用,9%~70%的IgAN患者血清IgA升高^[1],而其血清C3水平是否下降仍有争议。有日本学者发现,IgAN患者的血清IgA/C3比值有利于区分IgAN与非IgAN^[2,3]。并与疾病预后相关^[4]。为进一步探讨免疫反应和补体系统对IgAN发生、发展的影响,本研究对1999年至2005年本院收治的原发性IgAN和非IgAN患者的血清IgA、C3及IgA/C3比值进行分析,
出处 《诊断学理论与实践》 2009年第2期191-193,共3页 Journal of Diagnostics Concepts & Practice
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