摘要
目的:探讨苦碟子注射液联合阿司匹林治疗急性脑梗死的疗效。方法:112例脑梗死患者,随机分为治疗组(n=58)和对照组(n=54),分别给予抗脑水肿药物和脑保护剂,同时口服阿司匹林;治疗组在此基础上加用苦碟子注射液。分别于治疗前、后评价两组患者神经功能缺损情况,比较病情程度。结果:两组患者在用药后第7、14、21、28天神经功能缺损评分和日常生活活动Barthel指数与前一观察日有显著性差异。与对照组比较,治疗组患者神经功能恢复早,在用药后第21、28天有显著性差异。两组用药后无明显不良反应。结论:苦碟子注射液联合阿司匹林治疗脑梗死疗效确切,安全性好。
Objective: To evaluate efficacy of combination therapy of Kudiezi Injection and Aspirin in patients with acute stage cerebral infarction. Methods: The patients with cerebral infarction (n=112) were randomly divided into treatment group (n=56) and control group (n=54). Observation on clinical neurofunctional disorder and severity was carried out. Restilts: According to the Chinese Stroke Scale and the Barthel Score,we found that there were definite effectiveness and statistical signifieances in the patients of the two groups after the 7th, 14th,21st,28th days of treatment comparing to those prior to the treatment.There were also significant differences between the above two groups regarding the efficacies of Kudiezi and Aspirine miltiorrhiza at the 21st and 28th days, of which the improvement of Chinese Stroke Scale and the Barthel Score came earlier and being more effective in the treatment group since the 2nd day. Adverse reactions were modest in all patients. Conclusion: Combination of Kudiezi Injection and Aspirine is effective and safe in treatment of cerebral infarction in acute stage.
出处
《中国医药导报》
CAS
2009年第13期76-77,共2页
China Medical Herald
关键词
脑梗死
苦碟子
阿司匹林
Cerebral infarction
Kudiezi Injection
Aspirine