摘要
[目的]研究海带多糖对小鼠肠黏膜组织SIgA的影响。[方法]将40只昆明小鼠随机分为4组,分别以125、250、500μg/g的海带多糖灌胃小鼠15 d,以灌胃蒸馏水小鼠为对照,取小肠黏膜,采用试剂盒法测小肠黏膜组织的SIgA活性。[结果]250和500μg/g的海带多糖能够促进小鼠肠黏膜对SIgA的分泌量。[结论]海带多糖能够显著增强小鼠肠黏膜组织SIgA活性,并有随剂量增加活性增强的趋势。海带多糖对小鼠的免疫调节可能是通过肠道免疫系统发挥作用。
[ Objective] The study aims to research the effect of Laminarina japonica Polysaccharides （ LIPS） on intestinal immunity SIgA in mice.
[Method] The mice are fed with LJPS at doses of 250, 500μg/g. The effect of LIPS on intestinal immunity SIgA activity is evaluated in normal mice by EUSA box. [Result] LIPS 250 and 5（X） pg/g can enhance secretion of SIgA in mice, but it has no effect at 125 pg/g. [Conclusion] UPS increases activity of SIgA in mice and the activity increasing with dose of LJPS. The effect of UPS on intestinal immunity in mice may regulate the intestinal immunity system.
出处
《安徽农业科学》
CAS
北大核心
2009年第12期5515-5515,5520,共2页
Journal of Anhui Agricultural Sciences
基金
河北省教育厅科研项目(2006309)
