摘要
近年来的研究认为,动脉粥样硬化是一种慢性炎症性疾病。细胞因子不但参与了脂质条纹的形成过程:包括内皮细胞的受损、活化,各种趋化因子和黏附分子的分泌,单核巨噬细胞、淋巴细胞的聚集并向内膜下迁移,还参与了促使斑块破裂、血栓形成的整个过程。现就细胞因子在动脉粥样硬化发生、发展以及并发症中的作用的研究现状做一综述。
In the past few years, Chronic inflammation has emerged as a major driving force of atherosclerosis lesion development.Cytokines are not only involved in the formation of early fatty streak ,when the endothelium is actived and expresses chemokines and adhesion molecules leading to monocyte/lymphocyte recruitment and infiltration into the subendothelium,but also implicated in the process of leading to rupture of the plaque and thrombus information.The purpose of this review is to bring together the current information concerning the role of cytokines in the development,progression,and complications of atherosclerosis.
出处
《疾病监测与控制》
2009年第5期311-312,共2页
Journal of Diseases Monitor and Control
