摘要
儿童肥胖及代谢综合征患病率逐年增加。近年来研究发现脂肪组织可产生多种炎性反应因子，包括C反应蛋白、肿瘤坏死因子-α、自细胞介素-6等，导致机体发生慢性低度炎性反应，并在儿童和青少年生命早期促进代谢综合征、胰岛素抵抗及心血管疾患的发生和进展。因此，尽早监测肥胖儿童血清炎性反应因子并进行生活方式干预可有效降低相关疾病的进展。
The prevalence of overweight and metabolic syndrome is increasing in young people. Body fat produces a number of inflammatory cytokines, such as C-reactive protein, TNF-α, IL-6, etc, which lead to chronic subclinical inflammation. Chronic subclinical inflammation in childhood and adolescents is associated with obesity, which closely related with metabolic syndrome and insulin resistance at all ages. This feature of the diseases provides an opportunity for the early identification of target groups and the use of appropriate lifestyle intervention can effectively interrupt the pathological processes at early stages.
出处
《国际内分泌代谢杂志》
2009年第B04期63-65,共3页
International Journal of Endocrinology and Metabolism
关键词
儿童
肥胖
代谢综合征
炎症
干预
Children
Obesity
Metabolic syndrome
Inflammation
Prevention
