摘要
目的了解本地区哮喘儿童的变应原，为预防和治疗儿童哮喘提供依据。方法对我院2007年1月至2008年2月463例1～14岁哮喘患儿行变应原皮肤点刺试验，婴幼儿哮喘组126例，儿童哮喘组337例。变应原分为吸入组和食物组。结果哮喘患儿变应原皮肤点刺试验总阳性率高达96．3％，吸入组中尘螨阳性率最高38．2％，其次为室尘、柳树花粉等，尘螨强阳性率最高10．4％，其次为柳树花粉、室尘等。食物组中牛奶阳性率和强阳性率均最高，分别为34．6％、3．9％，其次为海虾、鸡蛋等。尘螨和牛奶阳性率在婴幼儿组和儿童组差异均有统计学意义（P〈0．05），尘螨和牛奶强阳性率在婴幼儿组和儿童组差异均无统计学意义（P〉0．05）。结论在过敏因素中吸入变应原是本地区儿童哮喘发作的主要因素，而尘螨、室尘、柳树花粉等又是吸入变应原中的主要变应原，在食物过敏因素中牛奶和海虾是婴幼儿哮喘发作不能忽略的重要因素。
Objective To investigate the allergen of asthmatic children of the local area,and provide a preventing and treating method for children with asthma. Methods Allergen skin prick test was performed on 463 asthmatic children of 1-14 years old in the hospital from January,2007 to February,2008. There were 126 cases with asthma in the infantile group,and 337 cases with asthma in the children group. The allergen could be classified into the inhaling group and the food group. Results The total positive rate of asthmatic children was up to 96. 3%. For the inhaling group,the positive rate of dust mites was the highest, which accounted for 38.2 %, the second was house dust, the third was the willow pollen and so on, the strongly positive rate of dust mites was also the highest, which was 10.4 %, the second was the willow pollen, the third was house dust and so on. For the food group,the positive rate and the strongly positive rate of milk were both the highest,which accounted for 34.6 % and 3.9 % respectively, the second was sea shrimp, the third was egg and so on. The differences of the positive rate of dust mite and milk between the infantile group and the children group both had statistical significance（ P 〈0.05） ,the differences of the strongly positive rate of dust mite and milk between the infantile group and the children group were both of no statistical significance（ P 〉0.05）. Conclusion Among the allergic factors, the inhaling allergens are the main factors at wheezing episodes in the local area,and dust mites,indoor dust, the willow pollen are the main allergens in the inhaling allergens,in the allergic factors of food,milk and sea shrimp are the importmant factors that could not be ignored to the infantile wheezing episodes.
出处
《临床荟萃》
CAS
2009年第10期872-875,共4页
Clinical Focus
关键词
哮喘
变应原
儿童
asthma
allergens
children
