摘要
随访“６·２５”６０Ｃｏ源辐射事故造成的ＡＲＳ５例５．５年各内分泌腺体的功能改变。方法主要用放射免疫法测定激素水平。结果急性期血睾酮明显减少、血ＴＴ３减少、血皮质醇可能因受地塞米松抑制而减少、血垂体激素（如ＡＣＴＨ等）也因照射而减少，而血雌二醇、ＰＲＬ、ＬＨ、ＦＳＨ等一度明显升高。至后期不同程度地逐渐恢复，并逐渐趋于平稳或趋于降低。肾素－血管紧张素－醛固酮系统反应活跃，一般以偏高居多。结论照射后各内分泌腺体功能改变较大，但至５．５年，除睾酮偏低，ＲＡＡ系统反应活跃外。
Objective\ The functional changes of endocrine glands in five cases of acute radiation sickness(ARS) were observed up to five and a half years after60~Co radiation accident.\ Methods \ Determinations of hormones were carried out by radioimmunoassay.\ Results \ The serum testosterone and total triiodothyronine levels were reduced significantly and plasma cortisol also decreased may be caused by the inhibition of administered dexamethasone.The radiation on the putuitary caused the decrease of pituitary hormones (ACTH,etc).But serum estradiol prolactin LH and FSH levels once elevated significantly.All these changes recovered gradually later to different extent.But the renin angiotensin aldosterone system had a very active,mainly hyperactivating,response.\ Conclusion\ Radiation had a siginificant effect on endocrine glands,but most of its changes were recovered five and a half years later,except the slight decrease of serum testosterone and hyperactivity of RAA axis.
出处
《中华放射医学与防护杂志》
CAS
CSCD
北大核心
1998年第1期43-48,共6页
Chinese Journal of Radiological Medicine and Protection
