摘要
目的评价海藻酸钠微球在子宫肌瘤动脉栓塞治疗中的应用价值。材料与方法3例多发性子宫肌瘤患者施行了超选择性子宫动脉栓塞术。所用栓塞剂为直径500μm-700μm海藻酸钠微球。对栓塞前后子宫肌瘤的大小、数量、临床症状及体征,以及卵巢激素水平进行比较。术后1个月、3个月进行B超随访,术后3个月进行卵巢激素测定。以后每隔1年B超随访。结果3例多发子宫肌瘤患者,年龄40岁、41岁、43岁(平均41.5岁)。治疗前与治疗后三个月卵巢激素水平无明显变化。栓塞后1个月时症状明显好转,肌瘤缩小平均40%,其中4个小肌瘤消失。术后三个月肌瘤缩小50～60%,有5个小肌瘤消失。临床症状完全消失。平均每例随访42个月,未出现新的肌瘤,残留肌瘤体积随时间延长,逐渐变小。栓塞不良反应主要为疼痛、恶心、呕吐及发热。无严重不良反应发生。结论海藻酸钠微球用于子宫肌瘤动脉栓塞治疗方便、安全、疗效确切。
Objective To evaluate the therapeutic effect of KMG in uterine artery embolization for uterine fibroids. Meterials and Methods： Three patients with multi-uterine fibroids were performed uterine artery embolization with KMG（300 m -700 m）. In all cases,the size, number, clinical symptom and sign of uterine fibroids, as well as the levels of ovary hormones were compared before and after artery embolization. The patients received sonographic follow-up at the frst and the third months after the embolization, and ovary hormones were measured three months after embolization. After that, they were followed up by US for every two years. Results： The ages of the patients were 40,41 and 43 years（mean age 41.5 years）. There was no significant change in level of ovary hormones before embolization and three months after embolization. The symptoms were improved during one month after embolization, the tumor size reduced 40% on average. In addition, four small tumors of them disappeared. At three months, the reduction reached 50%-60% and five of them disappeared With no clinical symptoms. All patients, who were followed up for 42 months on average,had no new tumors, while the rest fibroids were progressive reduction in size. The adverse reactions of embolization included pain, nausea, vomiting and fever. There were no serious adverse reactions. Conclusion： Artery embolization with KMG is a convenient, safety and effective method for the treatment of uterine fibroids.
出处
《当代医学》
2009年第11期194-196,共3页
Contemporary Medicine
关键词
肌瘤
子宫
动脉栓塞
放射学
介入性
Fibroids
uterine
Artery embolization
Radiology
interventional
