摘要
目的研究异丙酚、喷他佐辛用于人工流产术的镇痛效果、不良反应。方法无痛人流术的早孕妇女60例,孕期50～60天,ISA分级Ⅰ～Ⅱ级,随机分成两组,观察组(A组):静脉注射喷他佐辛30mg后静注1%异丙酚。对照组(B组):单纯1%异丙酚静注,病人入睡后手术。观察指标包括诱导时间、药量,苏醒、离院时间,异丙酚总用量,镇痛效果,生命体征和不良反应。结果观察组诱导时间、药量,异丙酚总用量明显少于对照组,苏醒、离院时间两组没有明显的差别,镇痛效果比较,观察组的优秀率达100%,对照组为40%,有显著差异,生命体征术前术后没有明显变化,无不良反应的发生。结论喷他佐辛复合异丙酚用于无痛人流术镇痛效果优于单纯异丙酚静注,值得临床推广使用。
Objective To evaluate the analgesic and adverse effects of disoprofol and pentazocine in painless artifical abortion.Methods Sixty women with a pregnant duration of 50-60days and an ISA grade Ⅰ-Ⅱ ,who volunteered to received a painless artifical abortion,were randomly assigned to two groups. women in group A were given anintravenous injection of pentazocine30mg followered by 1% disoprofol. The following items were observed：induction time,induction dose,the time ndeeded for awakening,the time needed for leaving the hospital,the total dosage of disoprofol,analgesic effects,the change of vital signs,and adverse events.Results：Compared with control group,the induction time for group Awas significantly shorter, and induction dose and the total dosage of disoprofol were lower.There was no significant difference in the time needed for awakening or leaving the hospital bdeween the two groups.The effective rate in groyp A was 100% compared with 40% in control group,find the difference was ststistically significant.No significant changes in vital signs were observed after abortion,and no adverse events were observed. Conclusion A combination of disoprofol and pentazocine in painless artifical abortion can shorten the time of induction,decrease the dose of pentazocine,get an analgesic effect superior to fnat of disoprofol alone.
出处
《当代医学》
2009年第12期103-104,共2页
Contemporary Medicine
关键词
喷他佐辛
异丙酚
人工流产术
镇痛
artifical abortion
disoprofol
pentazocine
analgesia
