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美沙酮维持治疗海洛因依赖者的生命质量及其影响因素研究 被引量:16

Quality of Life of Heroin Dependent Patients with Methadone Maintenance Therapy
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摘要 目的了解参加美沙酮维持治疗的海洛因依赖者的生命质量及其影响因素。方法在四川省自贡市社区药物维持治疗中心抽取216名海洛因依赖者进行问卷调查,问卷包括WHOQOL-BREF及影响生命质量的相关因素的条目。结果美沙酮门诊治疗者的得分为13.14±2.79(生理领域),12.17±3.38(心理领域),12.20±3.17(社会关系领域),11.94±3.31(环境领域),12.06±3.73(总的生存质量与健康状况)。单因素分析显示,年龄越大,吸毒年限越长,没有工作,与家人关系越差,过去3个月被抓,性生活越少,服用过安定,对治疗没有信心,各领域生命质量越差(P<0.05)。治疗6~12个月的患者环境领域的生命质量高于治疗6个月以内者(P<0.01)。注射与其他方式混用的患者生理领域的生命质量低于单纯口吸者(P<0.05)。多元逐步回归分析结果表明,美沙酮门诊治疗者生命质量的影响因素包括年龄、吸毒年限、是否工作、与家人关系、性生活频率、过去3个月是否被抓、是否服用安定、治疗的信心。结论应根据治疗者不同的个体和家庭情况,采取相应的措施提高其生命质量。 Objective To investigate the quality of life of heroin dependent patients with methadone maintenance therapy and its influencing factors. Methods A total of 216 heroin dependent patients who were receiving methadone maintenance therapy in Zigong of Sichuan Province were surveyed with the WHOQOL-BREF. Results The patients had a score of 12. 06±3. 73 for total quality of life and wellbeing and a score of, 13. 14± 2.79, 12. 17 ± 3. 38, 12. 20±3. 17, 11. 94 ± 3. 31, for physical, psychological, social relationships, and environmental function respectively. Age, length of drug addiction, job status, family relationship, arrested in last three months, frequency of sex activity, taking tranquilizer, confidence of treatment,duration of treatment, ways of using drugs had an impact on quality of life(P〈0. 05). Age, length of drug addiction, job status, family relationships, frequency of sex activity, arrested last three months, taking tranquilizer, and confidence of treatment entered into the multiple regression model. Conclusion It is vital to take measures to improve quality of life of the drug addicted patients according to their different individual and family status.
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2009年第3期539-543,共5页 Journal of Sichuan University(Medical Sciences)
基金 纽约中华医学会(CMB)AIDS性网络项目(82827601043)资助
关键词 美沙酮维持治疗 生命质量 影响因素 Methadone maintenance treatment Quality of life Influencing factors
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