摘要
对３８例多发性硬化（ＭＳ）患者和４１例正常人的交感神经皮肤反应（ＳＳＲ）与多方式诱发电位进行研究。结果：３８例确诊和近似确诊的ＭＳ患者ＳＳＲ异常率（８１．６％）比异常的诱发电位更为常见。在伴有自主神经症状的２１例ＭＳ患者中１９例ＳＳＲ异常（９０．５％），１７例无自主神经症状的ＭＳ患者中１２例ＳＳＲ异常（７０．６％）。提示：ＳＳＲ能客观有效地反映自主神经功能状态，检出ＭＳ的亚临床异常。将ＳＳＲ与多方式诱发电位联合评估ＭＳ中枢神经系统损害，具有更高的敏感性，有助于ＭＳ的早期诊断。
SSR and multimodality EPs were studied in 38 patients with MS and 41 normal persons. The results showed that SSR was abnormal in 31 patients(81.6%). Pathological SSR were more common than evoked patentials in definite and approximate definite MS.In 21 patients of MS with autonomic symptoms, SSR was abnormal in 19 patients(90.5%); in 17 patients without autonomic symptoms,SSR was abnormal in 12 patients(76.6%). It has closely relation between pathological SSR and MS. The results suggest that SSR can reflect objectively autonomic function. The abnormal in subclinical phase can be examined. The combination of SSR and multimodality EPs yields a higher sensitivity for the evaluation of MS centrel never system dysfunction than their individual yielde. It is contribute to the early diagnosis of MS.
出处
《临床神经病学杂志》
CAS
1998年第1期16-18,共3页
Journal of Clinical Neurology
关键词
多发性硬化
自主神经
SSR
病理
Multiple Sclerosis Sympathetic skin Response Autonomic never
