摘要
近年来,材料科学、组织工程学和纳米技术的快速发展使各种复合材料人工骨、组织工程构建人工骨相继研制成功。目前常用的骨修复材料包括自体骨和金属假体。自体骨虽然是理想的骨缺损修复材料,但自体取骨增加了患者的创伤和痛苦,并且供骨的来源有限,难以满足大段骨移植的要求;金属假体对缺口敏感,存在松动、断裂、组织相容性差、不可降解等问题。因此,研制理想的人工骨替代材料移植修复骨缺损,成为医学和组织工程学领域的研究重点。骨科置入体大量应用解决了骨科学术领域的许多难题,文章从股骨假体置入后应力、角度、组织相容性等学角度进行探讨,以便了解骨科置入体的生物及力学特性。
Recently, material science, tissue engineering and nanometer technique help development of various compound artificial bone and tissue-engineered bone. Autogenous bone and metal prosthesis are commonly used as bone repair materials. Autogenous bone is an ideal material to repair bone defect, however, autogenous bone harvest increases patient trauma and pain Moreover, its source is very limited, and it could not meet the requirement to repair large-segment transplantation. Metal prosthesis has problems such as sensitivity to defect, loosening, breakage, bad histocompatibility and nondegradation. Preparation of ideal bone substitutes to repair bone defects has become the focus of medical and tissue engineering field. Orthopedic implants have solved many difficulties in orthopedic surgery. This paper discussed stress, angle and histocompatibility of femoral prosthesis to well know biological and mechanical properties of orthopedic implants.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2009年第17期3316-3319,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
