摘要
目的探讨高压氧早期干预高危新生儿高胆红素血症的有效性。方法将32例符合研究对象标准的病例随机编号,分为二组(对照组和治疗组),治疗前都给予NBNA评分一次,两组均给予同样高胆红素血症常规治疗(包括光疗、药物或换血疗法等),治疗组同时配合婴儿高压氧舱治疗,每日一次,7天为一疗程。高压氧每完成一个疗程后即进行NB-NA评分,如于正常范围(>35分)则终止高压氧治疗;如NBNA评分异常(≤35分),则继续高压氧下一个疗程,高压氧总疗程为1-2个周期。两组出院时均进行一次NBNA评分。结果早期配合高压氧治疗NBNA评分异常的高胆红素血症在咯咯声反应、红球的反应、围巾征、腘窝角4项与仅予高胆红素血症常规治疗对比有显著差异(P<0.05)。结论高压氧早期治疗对高胆红素血症导致的行为能力影响有一定的干预作用。
Objective： To explore the effect of hyperbaric oxygen to the hyperbilirubinemia of newborn at the early stage. Methods： The 32 cases were divided into two groups （the control group and the treatment group）. The NBNA scores were given to all the cases before the treatment. Both of the group were given the conventional therapy of hyperbilirubinemia （ include the phototherapy/ medicine/or exchange transfusion）, the neonates the treatment group were given hyperbaric oxygen treatment, once daily, every 7 days was a course of treatment. It was necessary to give a NBNA score after each course, if the score 〉 35, stop the hyperbaric oxygen treatment, if the score≤35, continue the hyperbaric oxygen treatment, the total therapy course was 1 -2. All the patients in the both groups were given a NBNA score. Results： There were significance between the two groups in the gurgling sounds/red ball reaction/ scarf sign/and popliteal fossa angle. （ P 〈 0. 05 ） .Conclusion ： The early hyperbaric oxygen treatment may intent the capability resulted by hyperbilirubinemia.
出处
《中国优生与遗传杂志》
2009年第5期102-103,共2页
Chinese Journal of Birth Health & Heredity
关键词
高压氧
早期干预
高胆红素血症
Hyperbaric oxygen
Early intervention
Hyperbilirubinemia
