摘要
目的了解深圳市福田区出生缺陷的发生率及变化趋势、常见出生缺陷的种类及变化情况,为制定干预措施提供依据。方法对2003-2008年的出生缺陷监测资料进行回顾性分析。结果6年出生缺陷平均发生率为21.89‰,出生缺陷总发生率的变化呈逐步上升趋势(χ2=22.80,P=0.000),其中主要为流动人口出生缺陷发生率上升(χ2=23.67,P=0.000)。流动人口出生缺陷发生率高于常住人口(χ2=6.83,P=0.033)。出生缺陷前4位依次是先天性心脏病、多指(趾)、唇腭裂、外耳畸形,占出生缺陷的45.90%,其中先天性心脏病发生率和构成比呈上升趋势。结论深圳市福田区的出生缺陷发生率呈逐年上升趋势,应进一步提高产前诊断水平,特别是在妊娠28周前及时诊断和处理先天性心脏病,关注流动人口的孕期保健是降低出生缺陷的关键。
Objective： To understand the prevalence, major types of birth defect, So as to provide information for birth defect control. Methods： A database was analyzed retrospectively concerning birth defect monitoring from 2003 to 2008. Results： The average incidence of birth defects during the six years was 21.89%, and generally, the incidence in each year appeared an ascending trend （ χ^2 = 22. 80, P = 0. 000）. The incidence of birth defects in fluid population was higher than that in resident population （ χ^2 = 6. 83, P = 0. 033 ）. The first four birth defects were congenital heart disease, polydactylia, cheiloschisis/palatoschisis, and deformity of external ear in order. The incidence rate and constituent ratio of congenital heart disease appeared an ascending trend. Conclusion ： The incidence of birth defects of perinatal children in Futian district, Shenzhen city showed a rising trend. Should to promote the level of prenatal diagnosis consecutively, especially to diagnose and treat congenital heart disease before 28 week＇s pregnancy; Pay attention to the prenatal heath care in floating population, are related to decreases in overall infant mortality at the population level.
出处
《中国优生与遗传杂志》
2009年第5期111-113,共3页
Chinese Journal of Birth Health & Heredity
关键词
围生儿
出生缺陷
监测
分析
Perinatal baby
Birth defect
Monitoring
Analysis
