摘要
用人乳头瘤病毒（ＨＰＶ）通用引物（ＧＰ）及型特异性引物（ＳＰ）６、１１、１６、１８对４２例尖锐湿疣（ＣＡ）组织和４８例对照组进行多聚酶链反应（ＰＣＲ）检测。结果：ＣＡ组织五组引物扩增阳性率分别为８５．７％（３６／４２）、７３．８％（３１／４２）、１９．１％（８／４２）、２．４％（１／４２）、４．８％（２／４２），多重型别阳性率为１１．９％（５／４２）；对照组ＨＰＶ阳性率为６．３％（３／４８）。
The general primer (Gp) and type speicific primer (SP) 6、11、16、18 from human papillomavirus genomes were used to amplify 42 gential condyloma acuminatum (CA) biopsies and 48 normal cervical specimens with polymerase chain reaction (PCR).The results showed that the positive rates of the five primers to amplify CA biopsies were 85.7%(36/42)、73.8%(31/42)、19.1%(8/42)、2.4%(1/42)、and 4.8%(2/42),respectively.The positive rate of multiple types of HPV was 11.9%(5/42),the positive rate of GPHPV in normal group was 6.3%(3/48).The results indicated that HPV infection,partically HPV6,was associated with genital CA in Wen Zhou area.
出处
《中国皮肤性病学杂志》
CAS
北大核心
1998年第2期71-72,共2页
The Chinese Journal of Dermatovenereology
关键词
人乳头瘤病毒
尖锐湿疣
多聚酶链反应
Human papillomaviruses Condyloma acuminata Polymerase chain reaction
