摘要
目的调查甘肃省武威市农村居民甲型肝炎病毒（HAV）和乙型肝炎病毒（HBV）的流行状况。方法采用随机抽样方法调查4个乡镇539人;ELISA法检测调查人群血清中抗-HAV IgG和HBsAg,了解HAV和HBV的流行状况。结果居民中抗-HAV IgG阳性率为63.08%,低于全国平均水平,HBsAg阳性率为12.80%。11～20岁青少年抗HAV-IgG阳性率为83.33%,61岁～老年人阳性率为9.09%,明显低于其他人群（P〈0.05）。61岁～老年人中HBsAg阳性率为24.24%,明显高于41～60岁人群（10.07%和7.37%）（P〈0.05）。结论甘肃省武威市农村地区青少年HAV感染率高,61岁～居民对HAV的特异性免疫力低。人群中HBV感染率高。应进一步加强病毒性肝炎的健康教育和甲、乙型肝炎疫苗的预防接种工作。
Objective To study the prevalence of hepatitis A virus（HAV） and hepatitis B virus（HBV） infection among the rural people of Wuwei area. Methods A total of 539 people lived in villages and towns were chosen for the study. Anti-HAV IgG and HBsAg in serum were detected by ELISA. The prevalence rates of HAV and HBV among the people of different sex, age, education as well as incomes were compared. Results The positive rate of anti-HAV IgG （63. 08% ） in the was subjects lower than the averag level of the whole nation. The positive rate of HBV was 12. 08%. There was no difference in anti-HAV IgG and HBsAg positive rate among the people of different sex, education and incomes （P 〉0.05）. The positive rate of Anti-HAV IgG was higher among the people of 11 -20 years old（83.33% ） and it was significantly lower among the people of 61 - years old（9. 09% ） than the other age groups（ P 〈 0. 05 ）. The positive rate of HBsAg was significantly higher among people of 60 ＋ years old（24. 24% ） than the ages of 41 -60 years old（ P 〈 0. 05 ）. Conclusion The infection rate of HAV among the young people was high and the specific immunity against of HAV in the old people：≥60 years was lower and the infection rate of HBV was high among the rural people of Wuwei area. The health education on hepatitis and the vaccination of HAV and HBV need to be promoted.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2009年第5期620-621,共2页
Chinese Journal of Public Health
基金
兰州大学交叉学科青年创新基金(LZU200519)
