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从须纤恙螨分离到恙虫病立克次体的研究 被引量:1

First Isolation of Rickettsia Tsutsugamushi from Leptotrombidium Palpalis
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摘要 目的:研究纤须恙螨的恙虫病病原学意义及潜在媒介作用。方法:以71~150只左右须纤恙螨为一批接种小白鼠,共分4批。结果:均成功地分离到恙虫病立克次体。传代小鼠的临床症状有弓背、耸毛、厌食等,内脏仅见肝脏肿大,脾脏只在最初2代有个别肿大。IFA法检测传代阳性小鼠血清中的恙虫病立克次体IgG抗体,均呈阳性反应,血清分型结果均为Giliam型。对须1104株LD50测定结果为10-14375。结论:须纤恙螨是仅作为恙虫病立克次体的宿主,抑或既是宿主又可充当潜在媒介,在恙螨→人或恙螨→鼠之间起作用。 This article reported the isolation of Rickettsia tsutsugamushi (Rt.) from Leptotrombidium palpalis in China for the first time. 4 strains were obtained from 4 groups of chiggers (71-150 chiggers as a group). Enlargement of liver was observed in experimented mice inoculated with isolates, but the spleen′s enlargement was rarely observed. Serological identification of 4 strains revealed strong positive reaction with Rt. (Gilliam strain). More research was needed to confirm whether L.palpalis can act as a vector of Rt. from chiggers to rodents or from chiggers to men.
出处 《中国媒介生物学及控制杂志》 CAS CSCD 1998年第1期51-54,共4页 Chinese Journal of Vector Biology and Control
关键词 须纤恙螨 恙虫病 立克次体分离 病原体 L.palpalis Isolation of Rt.
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  • 1徐毛华,刘玉,鲍明荣,沈建中,吴光华,包知达,李峥,涂正银.南京恙虫病2例报告[J]江苏医药,1987(12).

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