摘要
目的观察丹红注射液对急性脑梗死患者血液流变学和血流动力学的影响及临床疗效。方法临床选取急性脑梗死患者随机为治疗组和对照组(各86例)。治疗组给予丹红注射液,对照组给予复方丹参注射液,两组患者均于治疗前后分别检测血液流变学的指标变化,采用经颅多普勒彩色超声(TCD)测定大脑中动脉血流速度(VMCA)并进行日常生活能力量表(ADL)评分和神经系统功能缺损评分(NIHSS),与对照组比较。结果治疗前两组受检者的血液流变学指标及大脑中动脉血流速度(VM-CA)和日常生活能力量表(ADL)评分及神经功能缺损程度评分(NIHSS)均无显著性意义(P>0.05);治疗后两组受检者的血液流变学指标和VMCA差别有显著性意义(P<0.05),ADL评分和NIHSS明显低于对照组,治疗组总有效率为88%。结论丹红注射液能明显改善急性脑梗死患者的血液流变学和血流动力学指标,并有良好的临床疗效。
Objective To investigate the effect of Danhong injection on hemorheology and hemodynamics of patients with acute cerebral infarction and it＇ s clinical efficacy. Methods The patients with acute cerebral infarction were randomly selected for the treatment and control group （86 cases）. The treatment group was treated with Danhong injection, and the control group with Danshen injection, the patients in both groups were detected the changes in hemodynamics before and after the treatment, compared with the control group in the blood flow velocity Of middle cerebral artery（VMCA） with tanscranial color Doppler（ TCD）, daily life ability （ADL） （ADL） score, and the National institute Of Neurological and Stroke （ NIHSS ）. Results There＇ s no significant defference in the hemodynamics, the blood flow velocity Of middle cerebral artery （VMCA） , daily life ability （ADL） （ADL） score ,and the National Institute Of Neurological and Stroke（NIHSS） （ P 〉0. 05 ） between two groups before the treatment. After the treatment , there＇ s significant defference in the hemodynamics and VMCA （P 〈 0. 05 ） , ADL and NIHSS score were significantly lower than control group＇ s, The treatment group＇ s total effective is 88%. Conclusions Danhong injection can be significantly improved the indicators of Hemorheology and hemodynamieso in the treatment of patients with acute cerebral infarction, and there＇ s a good clinical efficacy.
出处
《中国实用医药》
2009年第14期16-18,共3页
China Practical Medicine
关键词
急性脑梗死
丹红注射液
血液流变学
经颅多普勒
临床疗效
Acute cerebral infarction
Danhong injection
Hemorheology
Tanscranial Doppler
Clini- cal efficacy
