摘要
目的观察可吸收聚乳酸-替硝唑抗菌缓释剂局部治疗牙周炎的临床疗效。方法局部应用可吸收聚乳酸-替硝唑抗菌缓释剂治疗90例成人牙周炎患者,45例成人牙周炎患者口服替硝片剂为对照组,进行对比研究,检测治疗前后牙周炎的各项指数以及病变部位厌氧菌的变化。结果可吸收聚乳酸-替硝唑抗菌缓释剂局部治疗成人牙周炎的疗效显效率为93.3%,优于对照组73.3%。替硝唑局部给药对口腔厌氧菌的杀灭效果较口服替硝唑强,用药后无任何毒不良反应。结论可吸收聚乳酸-替硝唑抗菌缓释剂局部治疗牙周炎疗效显著,前景广阔。
Objective To observe the treatment effects of local Tinidazole buccal tablet to the patients with periodontitis. Methods 90 adults periodontitis were treated by local Tinidazole（TNZ） buccal tablet. 45 patients were treated by the tablets of Tinidazole served as control group. Results The effective rate of local Tinidazole buccal tablet in adult periodontitis patients was 93.3%, which was significantly higher than that of the control group（73.3% ）. Antimicrobial study showed that the action of Tinidazole buccal tablet to kill the periodontal dominant anaerobic bacteria was better than that of TNZ tablets, without any adverse effects. Conelutions It is suggested that the method of local Tinidazole buccal tablet has wide prospect in the treatment of periodontal disease.
出处
《中国实用医药》
2009年第14期30-31,共2页
China Practical Medicine
